A rare syndrome characterized by the presence of thickened yellow nails, lymphedema, and respiratory abnormalities, including pleural effusion, bronchiectasis, chronic sinusitis, and persistent cough. some cases are associated with mutations in the foxc2 gene.

Yellow nail syndrome, also known as "primary lymphedema associated with yellow nails and pleural effusion",: 849  is a very rare medical syndrome that includes pleural effusions, lymphedema (due to under development of the lymphatic vessels) and yellow dystrophic nails. Approximately 40% will also have bronchiectasis...