Thromboangiitis obliterans, also known as Buerger disease (English ; German: [ˈbʏʁɡɐ]) or Winiwarter-Buerger disease, is a recurring progressive inflammation and thrombosis (clotting) of small and medium arteries and veins of the hands and feet. It is strongly associated with use of tobacco products, primarily from smoking, but is also associated with smokeless tobacco. .