Post-transplant lymphoproliferative disorder (ptld) is a polyclonal (benign) or clonal (malignant) proliferation of lymphoid cells that develops as a consequence of immunosuppression in a recipient of a solid organ or bone marrow allograft. ptlds comprise a spectrum ranging from early, epstein-barr virus (ebv)-driven polyclonal lymphoid proliferations to ebv-positive or ebv- negative lymphomas of predominantly b-cell or less often t-cell type. (who, 2001)

Post-transplant lymphoproliferative disorder (PTLD) is the name given to a B cell proliferation due to therapeutic immunosuppression after organ transplantation. These patients may develop infectious mononucleosis-like lesions or polyclonal polymorphic B-cell hyperplasia...