Fibrous dysplasia presenting as a single bone lesion.

Monostotic fibrous dysplasia is a form of fibrous dysplasia where only one bone is involved. It comprises a majority of the cases of fibrous dysplasia (approximately 70–80%). It is a rare bone disease characterized by the replacement of normal elements of the bone by fibrous connective tissue, which can cause very painful swellings and bone deformities, and make bone abnormally fragile and prone to fracture. A congenital, noninherited, benign anomaly of bone development in a single bone, it consists of the replacement of normal marrow and cancellous bone by immature bone with fibrous stroma...