Condition in which there is a deviation from or caused by an abnormal metabolic process; can be congenital due to inherited enzyme abnormality (inborn metabolism disorder) or acquired due to disease of an endocrine organ or failure of a metabolically important organ such as the liver.

A metabolic disorder is a disorder that negatively alters the body's processing and distribution of macronutrients, such as proteins, fats, and carbohydrates. Metabolic disorders can happen when abnormal chemical reactions in the body alter the normal metabolic process...