An idiopathic syndrome characterized by one or more of the following; recurrent orofacial swelling, relapsing facial paralysis, and fissured tongue (lingua plicata). the onset is usually in childhood and relapses are common. cheilitis granulomatosa is a monosymptomatic variant of this condition. (dermatol clin 1996 apr;14(2):371-9; magalini & magalini, dictionary of medical syndromes, 4th ed, p531)